PASTA

  • Alexander Miguel Monzon

    Alexander Miguel Monzon

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    ACADEMIC PROFILES SOCIAL REPOSITORIES CONTACTS +39 049 827 7964 alexander.monzon@unipd.it BioComputing UP

  • Damiano Piovesan

    Damiano Piovesan

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    ACADEMIC PROFILES SOCIAL REPOSITORIES CONTACTS +39 049 827 6260 +39 049 827 6269 damiano.piovesan@unipd.it BioComputing UP

  • Silvio C. E. Tosatto

    Silvio C. E. Tosatto

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    Group Leader ACADEMIC PROFILES SOCIAL REPOSITORIES CONTACTS +39 049 827 6260 +39 049 827 6269 silvio.tosatto@unipd.it BioComputing UP

  • Protein aggregation

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    The formation of amyloid aggregates upon protein misfolding is related to several devastating degenerative diseases. We developed PASTA to predict the propensities of protein sequences to aggregate into amyloids. These propensities represent the presence of aggregation hot spots stabilizing pathological interactions, the establishing of cross-amyloid interactions between co-aggregating proteins and the stability of the amyloid…