Our research concentrates in the fields of bioinformatics and computational biology, with a special emphasis on the structural and mechanistic aspects of complex systems. The research activities carried out at the BioComputing UP lab focus on two main pillars:
- development of novel methods, tools and databases to study proteins at different levels (sequence, structure, folding, function, interactions)
- application of methods to solve biologically relevant questions in different contexts.
Our staff is conducting cutting-edge research on structural and functional biology, large scale and genome wide analyses, genetic disease and cancer studies. The BioComputing UP is integrated in a wide international network: not only does it lead and coordinate several international consortia (NGP-net, IDPfun, REFRACT), but also it is actively involved in the ELIXIR research infrastructure, participating in the activities of the national Node, Data and Interoperability platforms, IDP User Community and Machine Learning Focus Group.